amyotrophiclateralsclerosis相关论文
目的:基于MRI应用独立成分分析和双回归结合的方法，探索肌萎缩侧索硬化症（ALS）患者大尺度运动及认知相关网络功能变化，及其与运动、认......
Amyotrophic lateral sclerosis is a relentlessly progressive multi-system condition. The clinical picture is dominated by......
核内不均一核糖核蛋白属于RNA结合蛋白中的一类，具有高度保守的结构。其中，核内不均一核糖核蛋白A2/B1(hnRNPA2/B1)参与转录、翻译等......
Unraveling pathological mechanisms in neurologicaldisorders: the impact of cell-based and organoid m
Cell-based models are a promising tool in deciphering the molecular mechanisms underlying the pathogenesis of neurologic......
Amyotrophic lateral sclerosis is a motor neuron degenerative disease that is also known as Lou Gehrig\'s disease in th......
Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies f
Fundamental organelles that occur in every cell type with the exception of mammalerythrocytes, the mitochondria are requ......
MicroRNA expression in animal models of amyotrophic lateral sclerosis and potential therapeutic appr
A review of recent animal models of amyotrophic lateral sclerosis showed a large number of miRNAs had altered levels of ......
Protein synthesis modulation as a therapeutic approach for amyotrophic lateral sclerosis and frontot
Protein synthesis is essential for cells to perform life metabolic processes. Pathological alterations of protein conten......
Frontotemporal lobar degeneration describes a group of progressive brain disorders that primarily are associated with at......
Amyotrophic lateral sclerosis is the most common adult-onset neurodegenerative disease affecting motor neurons. Its defi......
Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic
The onset and mechanisms underlying neurodegenerative diseases remain uncertain. The main features of neurodegenerative ......
目的:对1例肌萎缩侧索硬化症(amyotrophic lateral sclerosis, ALS)患者进行致病基因变异分析，明确其可能的致病原因。方法:收集患......
The neutrophil-to-lymphocyte ratio (NLR) is considered a robust prognostic biomarker for predicting patient survival out......
Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amy
The development of amyotrophic lateral sclerosis (ALS) may be related to the abnormal alterations of multiple proteins. ......
Ultra-early amplitude decrement after repetitive nerve stimulation supports early neuromuscular junc
The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral scler......
Lower and upper motor neuron involvement and their impact on disease prognosis in amyotrophic latera
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by progressive muscle wasting, breathin......
Creatine kinase in the diagnosis and prognostic prediction of amyotrophic lateral sclerosis: a retro
Creatine kinase is a muscle enzyme that has been reported at various levels in different studies involving patients with......
Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/ Frontotemporal Dementia Causes Neurotoxici
GGGGCC repeat expansions in the C9ORF72 gene are the most common cause of amyotrophic lateral sclerosis and frontotempor......
Hydrogen peroxide at low concentrations triggers the fibrillization of wild-type SOD1 via sulfenic a
Amyotrophic lateral sclerosis(ALS)involves the fibrillization of copper,zinc superoxide dismutase(SOD1)and TAR DNAbindin......
Antioxidant Effects of Celastrol Against Hydrogen Peroxide-Induced Oxidative Stress in The Cell Mode
Amyotrophic lateral sclerosis(ALS)is a common adult onset motor neuron(MN)disease leading to rapidly progressive degener......
Neurons derived from induced pluripotent stem cells(iPSCs)are increasingly employed to model human neurological diseases......
Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patient
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Epidemiology and factors predicting survival of amyotrophic lateral sclerosis in a large Chinese coh
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Quantitating Changes in Jitter and Spike Number Using Concentric Needle Electrodes in Amyotrophic La
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Pattern Differences of Small Hand Muscle Atrophy in Amyotrophic Lateral Sclerosis and Mimic Disorder
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Monitoring Value of Multimodal Magnetic Resonance Imaging in Disease Progression of Amyotrophic Late
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Single-nucleotide Polymorphism rs2275294 in ZNF512B is not Associated with Susceptibility to Amyotro
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Increased Orexin Expression Promotes Sleep/Wake Disturbances in the SOD1-G93A Mouse Model of Amyotro
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Association between DPP6 polymorphism and the risk of sporadic amyotrophic lateral sclerosis in Chin
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Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patient
Background::Investigations of the pathogenic mechanisms in motor neurons (MNs) derived from amyotrophic lateral sclerosi......
Epidemiology and factors predicting survival of amyotrophic lateral sclerosis in a large Chinese coh
Background::Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder associated with loss of motor neur......
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BACKGROUND: Affected signal convection of synaptophysin on motor neurons may Cause injury of motor neurons and then indu......
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Proximal-distal motor unit number estimation-dynamic changes in patients with amyotrophic lateral sc
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Changes in somatosensory evoked potentials elicited by stimulation of upper-limb and lower-limb nerv
This study observed the changes in somatosensory evoked potentials between patients with amyotrophic lateral sclerosis (......
